Proteasome Inhibitor

Proteasome inhibitors are an important class of drugs for the treatment of multiple myeloma and mantle cell. Proteasome inhibitors such as bortezomib carfilzomib and NPI-0052 are able to stabilize proapoptotic members of the p53 and Bcl-2 families and inhibit two major.

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What are Proteasome inhibitors.

Proteasome inhibitor. Proteins to be destroyed are recognized by. Proteasomes are protease complexes which are responsible for degrading endogenous proteins.

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